Recombinant Rabbit Secretory Immunoglobulin Molecules: Alpha Chains with Maternal (Paternal) Variable-Region Allotypes and Paternal (Maternal) Constant-Region Allotypes
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چکیده
منابع مشابه
Nonallelic behavior of rabbit variable-region allotypes
Group a allotypes not detected by qualitative typing or anticipated from breeding data (latent allotypes) were detected at low levels in 50% of normal rabbit sera tested. The latent allotypes, which were serologically identical to allotypes of pooled IgG, were detected in sera from rabbits with all possible combinations of group a allotypes and their occurrence in individual rabbits was transit...
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morethanoneclassofheavychainflodd, 1963)couldonlyberationalized if these markers were present in the variable region. This has been the subject of muchcontroversy, as the presence of a genetic marker is indicative that the gene bearing it is present as only a single entity in the germ line, and hence an argument for somatic mutation as the mode of generation of antibody diversity. Sequence stud...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1974
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.71.4.1169